Antiphospholipid Syndrome (aPL) This disease can have serious effects in pregnancy, both for the mother and the baby. These include strokes, blood clots, and recurrent miscarriage. Myasthenia Gravis and Pregnancy Pregnant women with MG often have more weakness and fatigue because of the added weight and effort of pregnancy. Preterm labor (labor before 37 weeks of pregnancy) is more likely. Systemic Lupus Erythematosus (Lupus) Most people who have lupus are young women. The effects of the disease can range from mild to severe.