Sexually Transmitted Diseases in Adolescents STDs are among the most common infectious diseases in this country—the United States has the highest rates of STDs in the industrialized world. Sexually Transmitted Diseases Women suffer more frequent and severe symptoms from STDs. Some STDs can cause pelvic inflammatory disease, which can lead to both infertility and ectopic pregnancy. Safer Sex Guidelines for Adolescents The only safe sex is no sex, most health care providers say. But certain precautions and safe behaviors can minimize a person's risk of contracting a sexually transmitted disease. Chlamydia Can Lead to Infertility A lot of us don't realize that chlamydia and other sexually transmitted diseases (STDs) can cause no symptoms, meaning you could have an STD and not know it. Answers to Questions About HPV Learning about HPV can help you avoid infection and seek treatment, if necessary.